Genetics: hereditary traits

Gene Expression

Single Nucleotide Polymorphism

The scientific term for a mutation in a DNA sequence is single nucleotide polymorphism, or SNP. We know that people with specific SNPs (“snips”) that affect the production of enzymes for handling the B vitamins or sulfur are more likely to have heart disease, brain disease, mood problems, and/or autoimmune problems. It is often possible, however, to overcome problem enzymes by using a specific nutritional regimen once we know which enzymes are affected and which vitamins and which forms of the vitamins or foodstuffs can help the person bypass that particular SNP. If a disease or condition runs in your family, that’s a sign that you and your relatives might have a particular SNP. A functional medicine doctor can make some predictions about the SNPs based on family history and genetic testing, and can recommend a personalized plan of action.